RECURRENT PREGNANCY LOSS

Pros & Cons: Recurrent Pregnancy Loss Genetic Testing

Everyone who is deciding whether to have genetic testing for recurrent pregnancy loss should first ask:

  • "Why am I getting tested?"
  • "What will this test mean for me?"
  • "What are the benefits of testing?"
  • "Are there any implications I should consider?"

Pros

These are very personal decisions. Here are just some of the reasons people choose to have genetic testing for recurrent pregnancy loss:

  • You've been diagnosed with recurrent pregnancy loss, but standard physical and laboratory tests have failed to find a cause.
  • You are curious whether a genetic condition has caused your miscarriages.
  • You are attempting to start a family at a late age and want to quickly discover if you might encounter problems carrying a baby to term.
  • You want reassurance that you did not cause your lost pregnancies.
  • You are seeking hope that continued efforts will be successful.
  • You want to confirm that it is time to consider alternative options such as egg or sperm donation, surrogacy, or adoption.
  • Having knowledge of a mutation means you can monitor your pregnancy and screen for it.

Cons

Here are some reasons people decide against genetic testing for recurrent pregnancy loss:

  • The tests offered do not provide an absolute "yes" or "no" answer in all cases. A positive result may indicate that genetics is just one of multiple factors responsible for your miscarriages, and a negative result does not necessarily mean that there is not a different genetic cause.
  • Knowing the cause of your miscarriages may not always increase your chances of achieving a successful pregnancy.
  • You fear you would feel guilty or angry that you have a genetic condition and are concerned about how you will react to your test results.
  • You worry that a positive test result will change your self-image or cause your loved ones to treat you differently.
  • You are concerned about genetic discrimination when obtaining medical or life insurance or employment.(Genetic testing through DNA Direct is an option for people with this concern. Our testing service is completely confidential and test results do not go into your medical record.)
  • You are concerned about the cost of testing and whether your insurance would cover the cost.
  • You are concerned that you may find out information about yourself that has implications beyond fertility. For example:
    • A positive test for the factor V Leiden or prothrombin gene may mean that you are at increased risk of blood clots.
    • A positive chromosome analysis may uncover a genetic change that runs in the family and can affect other relatives.

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