DNA Direct: Your Genes in Context

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Testing for Drug Response

Related Genetic Tests

CYP450 Genes

Includes a personalized report, a letter for your doctor, and toll-free support

Price: $250.00 - $630.00

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Pre-test & Post-test Consultation

Our genetic experts can counsel you before and after testing.

Price: $250 per hour

Call to schedule: 1-877-646-0222

Related Genetic Tools

Drug Response Test Finder

Over half of all medications are affected by 3 genes that you can test for: CYP 2D6, 2C9 and 2C19. This tool to see which drugs are affected by these genes.

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THE CYP450 GENES

What Testing for CYP450 Drug Response Tells You

Test results can help your doctor find the right drug — at the right dose — for you.

If You Test Positive (Poor or Ultra Metabolizer)

If you have experienced adverse drug reactions or had medications that didn't work for you in the past, positive test results may explain why. Test results can also help your doctor select safer and more effective treatment for you in the future. Positive results can help you and your doctor:

Avoid medications that may be problematic for you (see Drugs to Test For )
Adjust the dose if you need to take an indicated medication. For example, Poor Metabolizers might need to reduce a dosage, while Ultra Metabolizers might need to increase a dosage.
Be alert for side effects and/or lack of therapeutic effects.
Be alert for drug-drug interactions. Taking two drugs at the same time that you cannot metabolize effectively, can cause a serious adverse drug reaction.
Be extra careful about taking medication during pregnancy and nursing. Medication that you take may affect your baby.

If You Test Negative (Normal Metabolizer)

"Normal" test results mean that you are likely to have a standard response to the standard dose of medications processed by these genes.

A normal result does not guarantee that a medication will always work for you, however. Each person’s drug response may be influenced by a number of factors, including their age, gender, liver and kidney health, other medications, lifestyle, environment, and other genes that have not yet been identified.

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