DNA Direct: Your Genes in Context
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Testing for Drug Response
A HUMAN TOUCH
Our Genetic Experts
Genetic tests personalized to you backed by our expert insights.
Meet Andi Ybarra, M.S., CGC
Senior Genetic Counselor
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DNA Spotlight
DNA Archive™
FEATURED ARTICLE
Drug Metabolism and Ancestry
The likelihood that someone is a Poor Metabolizer (PM) or an Ultra Metabolizer (UM) depends, to some degree, on that person's genetic heritage. It is important to realize that the distribution of these gene variants may differ significantly between groups that people might otherwise consider the same ethnicity. For example, Ethiopians have very high rates of 2D6 Ultra Metabolizers, while South Africans have very high rates of 2D6 Poor Metabolizers.
The table below lists common drug metabolism gene variants and their frequencies in major ethnic groups.
WARFARIN RESPONSE TESTING & GENETICS FEATURE
What Is Warfarin?
in this Section
TAMOXIFEN RESPONSE TESTING & GENETICS FEATURE
What Is Tamoxifen?
A simple test can help you and your doctor choose drugs that are safe and effective for you. Avoid adverse drug reactions. Learn about genetic testing for drug metabolism. Pharmacogenetics.
in this Section
