The ColoSure™ stool DNA test is a state-of-the-art test designed to detect colon cancer early — when it's most treatable.

ColoSure™ does not diagnose colon cancer, it is a screening test. All cancer cells have DNA changes, called mutations, that happen when a cancer develops. These DNA changes are usually only found in cancer. When a cancer grows in the colon, it sheds cells into the stool. ColoSure examines a stool sample for a DNA change that is associated with colorectal cancer.

Watch a short film that explains how the ColoSure™ stool DNA test works:

Video: How Stool DNA Testing Works

ColoSure™ looks for a DNA change in the vimentin gene. The exact job of the vimentin gene in the body isn’t completely clear right now, but research shows that it is important to immunity and other important cell processes.

ColoSure™ determines if the vimentin gene is "turned on." If it is "turned off", or hyper-methylated, this could indicate colon cancer. The vimentin gene is turned off in about 72-77% of people with colon cancer.

The results of a ColoSure™ stool DNA test are typically either positive or negative.

• Negative Results: This test result is reassuring. Your next step is to share this result with your healthcare provider and talk about when to schedule your next routine screening. Schedule a Screening Reminder
• Positive Results: The DNA in the vimentin gene has been "turned off" (methylated). This has been associated with colon cancer but does not diagnose colon cancer. Your next step is to see your doctor for immediate follow-up. Follow-up may include a colonoscopy, which is the best test for diagnosing colorectal cancer.
  

* The ColoSure™ stool DNA test is not intended to replace colonoscopy. It should not be used by people who have symptoms, because they may need a test that provides a view of the tissues, such as colonoscopy.