RECURRENT PREGNANCY LOSS

Fast Facts: Recurrent Pregnancy Loss Genetic Testing

Genetic testing for recurrent pregnancy loss can help you:

  • identify treatments that can help you carry a pregnancy to term
  • find peace-of-mind by identifying the potential cause of previous losses
  • decide whether to consider alternative options such as egg or sperm donation, surrogacy, or adoption

Fast facts:

  • Doctors say that a woman is experiencing recurrent pregnancy loss if she has had three miscarriages, or two miscarriages in a row.
  • Miscarriage is a very common occurence. The earlier that we are able to detect pregnancies, the more miscarriages are detected:
    • 40 percent of pregnancies detected by a blood test end in miscarriage.
    • 25 percent of pregnancies detected by a fetal heart beat end in miscarriage.
  • Miscarriages are so common that researchers believe that as many as 50% of all pregnancies end in miscarriage if the earliest possible methods of detection were used and all miscarriages were reported to doctors.
  • The risk of miscarriage increases as a woman gets older. This is believed to be related to the quality of the eggs (as opposed to other physical factors), because pregnancies that result from eggs donated by younger women carry the miscarriage risk of the younger woman rather than the older surrogate.
  • Between 5 and 7 percent of Caucasians (white people of European descent) have the factor V Leiden gene, which causes a blood clotting disorder that can contribute to recurrent pregnancy loss in women. This genetic change is less common in other ethnicities.
  • 1 in 20 couples who have recurrent pregnancy loss have chromosomal rearrangements or inversions that can contribute to recurrent pregnancy loss.
  • These days, being diagnosed with recurrent pregnancy loss doesn't mean that you will never have a baby. Outcomes depend on the causes you have and the treatments you choose.

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