There are many options for managing Alpha-1 antitrypsin deficiency. Some can be done on your own, such as lowering your exposure risks. Others are treatments that must be prescribed or coordinated by a doctor.
Treatments and screening procedures depend on whether or not you show evidence of Alpha-1-related lung or liver disease. Specific recommendations should be discussed with your doctor.
Taking steps to improve overall health is good for everyone, but it is especially important for people with Alpha-1. Lifestyle measures you can take are:
- Stopping smoking
- Minimizing your exposure to secondhand smoke (this is especially important for children)
- Avoid or limit alcohol consumption
- Avoid exposure to infections
- Avoid environmental or workplace exposure to:
- Dust and allergens (coal, minerals, hay, pollen)
- Gases and fumes (wood-burning stoves, kerosene, chlorine, ammonia)
- Chemicals (pesticides, some household cleaning products)
- Get regular screening to ensure early detection and treatment (see below)
- Get vaccinated
- Exercise regularly and eat well
Professional screening recommendations include:
- Regular physical exams with a doctor
- Learning to recognize early signs and symptoms of lung infections
- Periodic lung function tests
- Periodic liver function tests
- Ultrasound or CT scans for those over 50 years old
References:
American Thoracic Society/European Respiratory Society Statement: Standards for the Diagnosis and Management of Individuals with Alpha-1 Antitrypsin deficiency. Executive Summary. 2003. Am Jnl Resp and Crit Care Med 168(7).
Stoller, J. 2003. Key Current Clinical Issues in Alpha-1 Antitrypsin Deficiency. Respiratory Care 48(12): 1216-1224.




