Many insurance policies will cover genetic testing for Alpha-1. When you test with DNA Direct, we provide the support you need to seek reimbursement.
How to Apply for Reimbursement
Insurance Coverage
Anonymity
Insurance Company Websites
How to Apply for Reimbursement
To secure reimbursement for the cost, most insurance companies will ask you for the following:
- Invoice and Receipt. DNA Direct will email you a receipt after you order a test.
- CPT Codes. These codes tell the company what lab work was done, and how much their policy will pay for it. CPT Codes for Alpha-1 Testing
- Reimbursement Form. Each insurance company has their own form. Call your company to request this form. If you need help filling it out, you can call our Customer Service at the number and we will assist you.
- Letter of Medical Necessity. Some insurance companies will ask for a letter from your doctor that confirms this testing is medically important. You can phone your doctor's office to request this. If your doctor has a question, they can call our Clinical Director at the number below. See Sample Letter (.PDF)
- ICD-9 Codes. These codes specify a medical diagnosis. Your doctor will need to provide these codes. If a letter of medical necessity is required, ICD-9 codes can be included in the letter.
Insurance Coverage
Insurance policies usually cover testing according to medical necessity. So, some policies will reimburse you for Alpha-1 testing if you are testing for any of the following reasons:
- You have a family history of Alpha-1
- You have a diagnosis of Alpha-1 by "phenotyping" (protein testing)
- You have signs and symptoms of Alpha-1 such as emphysema, COPD, or unexplained liver disease
Insurance coverage will depend on your individual policy. If insurance coverage is necessary for you to test, you can call your insurance company's customer service line before testing to secure pre-authorization. List of Insurance Company Websites
For insurance questions or assistance, call Customer Service at 1-877-646-0222.
Anonymity
Some of our customers prefer to test through DNA Direct and not use insurance, in order to keep their testing and test results off their medical record. DNA Direct's secure system separates billing and clinical information, so the testing lab only sees your Order ID, not your name. We do not share your information with any third party without your written permission.
Insurance Company Websites
- Aetna
- Blue Cross Blue Shield
- Cigna
- Group Health Cooperative
- Group Health Incorporated
- Guardian Life Insurance
- Health Net
- Humana
- Kaiser Permanente
- Medica
- Oxford Health Plans
- PacifiCare
- UniCare
- United HealthCare




